Retransfusion acidosis after brief haemorrhagic hypotension in the dog

Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; conc...

Full description

Saved in:
Bibliographic Details
Published inActa chirurgica Academiae Scientiarum Hungaricae Vol. 17; no. 2; p. 161
Main Authors Takács, L, Szántó, G, Vándor, E
Format Journal Article
LanguageEnglish
Published Hungary 1976
Subjects
Acidosis - etiology
Animals
Blood Pressure
Blood Transfusion, Autologous
Carbon Dioxide - blood
Dogs
Female
Hemorrhage - complications
Hydrogen-Ion Concentration
Hypotension - complications
Lactates - blood
Male
Oxygen - blood
Online AccessGet more information

Cover

More Information
Summary:Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; concurrently, PaCO2 rose by 9.2-12.9 mm Hg. A close correlation was demonstrated between these changes. After retransfusion, PaO2 and the arterial lactic acid level did not change significantly. Thus retransfusion acidosis in the dog appears after a brief hypotensive period, too, but cannot be attributed to a "washout" of lactate from the tissues.
ISSN:0001-5431