Retransfusion acidosis after brief haemorrhagic hypotension in the dog
Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; conc...
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Published in | Acta chirurgica Academiae Scientiarum Hungaricae Vol. 17; no. 2; p. 161 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Hungary
1976
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Subjects | |
Online Access | Get more information |
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Summary: | Dogs under chloralose anasthesia were bled at a rate of 50 ml/min to a total of 25 ml/kg body weight and 2 minutes later a quick reinfusion of adequate volumes of blood, dextran, or Locke's solution was done. Within 2 minutes after reinfusion, the pH of arterial blood fell by 0.074--0.127; concurrently, PaCO2 rose by 9.2-12.9 mm Hg. A close correlation was demonstrated between these changes. After retransfusion, PaO2 and the arterial lactic acid level did not change significantly. Thus retransfusion acidosis in the dog appears after a brief hypotensive period, too, but cannot be attributed to a "washout" of lactate from the tissues. |
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ISSN: | 0001-5431 |