Psychiatric Uses of Gabapentin

ObjectiveThis article reviews evidence-based psychiatric uses of gabapentin, along with associated risks. Method of ResearchAn extensive literature review was conducted, primarily of articles searchable in PubMed, relating to psychiatric uses, safety, and adverse effects of gabapentin. ResultsEviden...

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Published inInnovations in clinical neuroscience Vol. 19; no. 7-9; pp. 55 - 60
Main Authors Martin, Jon C, Gainer, Danielle
Format Journal Article
LanguageEnglish
Published Matrix Medical Communications 01.07.2022
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Review
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Summary:ObjectiveThis article reviews evidence-based psychiatric uses of gabapentin, along with associated risks. Method of ResearchAn extensive literature review was conducted, primarily of articles searchable in PubMed, relating to psychiatric uses, safety, and adverse effects of gabapentin. ResultsEvidence supports gabapentin as a treatment for alcohol withdrawal and alcohol use disorder. There is sufficient evidence to consider gabapentin as a third-line treatment for social anxiety disorder and severe panic disorder. Evidence does not support the use of gabapentin for bipolar disorder, major depressive disorder (MDD), posttraumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), stimulant use disorder, or opioid withdrawal. Risks of gabapentin use are highest among those with a history of a substance use disorder and those concurrently taking opioids. ConclusionWhile gabapentin has a place in psychiatry for a select few indications, the literature does not support its use for many studied diagnoses.
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DISCLOSURES: The authors have no conflicts of interest relevant to the content of this article.
FUNDING: No funding was provided for this article.
ISSN:2158-8333
2158-8341