In Vivo Characterization of Oral Multiparticulate Systems

Formulation development of pharmaceutical multiparticulates requires in vivo performance validation which can be achieved with real-time imaging techniques such as gamma scintigraphy and magnetic resonance imaging either as stand-alone methods or in combination with complementary investigations such...

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Bibliographic Details
Published inMultiparticulate Drug Delivery pp. 359 - 386
Main Author Hodges, Lee Ann
Format Book Chapter
LanguageEnglish
Published United States Springer 2017
Springer New York
SeriesAdvances in Delivery Science and Technology
Subjects
characterization
Gamma scintigraphy
Gastrointestinal physiology
Gastroretention
Imaging
IntelliCap
Magnetic resonance imaging
Mini-tablets
Multiparticulates
Pharmaceutical technology
Radiolabeling
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Summary:Formulation development of pharmaceutical multiparticulates requires in vivo performance validation which can be achieved with real-time imaging techniques such as gamma scintigraphy and magnetic resonance imaging either as stand-alone methods or in combination with complementary investigations such as pharmacokinetic sampling and pH and temperature measurements using sophisticated swallowable electronic devices.
ISBN:9781493970100
1493970100
ISSN:2192-6204
2192-6212
DOI:10.1007/978-1-4939-7012-4_14