Clinical Presentation of Nonsclerotic Epidermal Chronic Graft-Versus-Host Disease and Hair and Nail Changes

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy for a wide variety of malignant and nonmalignant conditions, but the development of graft-versus-host disease after transplantation may cause significant morbidity and mortality. The updated National Institut...

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Bibliographic Details
Published inAtlas of Graft-Versus-Host Disease pp. 69 - 91
Main Authors Pinney, Sarah S., Alousi, Amin M., Hymes, Sharon R.
Format Book Chapter
LanguageEnglish
Published Switzerland Springer International Publishing AG 2017
Springer International Publishing
Subjects
cGVHD
Chronic graft-versus-host disease
Dermatology
Epidermal cGVHD
Hematopoietic stem cell transplantation
Oncology
Surgical oncology
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Summary:Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy for a wide variety of malignant and nonmalignant conditions, but the development of graft-versus-host disease after transplantation may cause significant morbidity and mortality. The updated National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease (cGVHD) [1] clarified and built upon the 2005 NIH Consensus Conference criteria for diagnosing and scoring the severity of chronic GVHD [2]. The purpose of these guidelines is to create uniformity in clinical trials, to guide treatment, and to facilitate biomarker studies.
ISBN:9783319469508
3319469509
DOI:10.1007/978-3-319-46952-2_7