Effect of armin on frog myelinated nerve fibers

Study of the action of armin on the nodes of Ranvier in isolated nerve fibers of the frog has demonstrated that armin at concentrations over 4 X 10(-7) M produces the growth of the input resistance of the nodes of Ranvier at the expense of the decreased leakage conduction. At concentrations of 4 X 1...

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Bibliographic Details
Published inBiulleten' eksperimental'noi biologii i meditsiny Vol. 96; no. 10; p. 76
Main Authors Vinogradova, I M, Kuleshov, V I, Matiushkin, D P, Sanotskiĭ, V I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.10.1983
Subjects
Action Potentials - drug effects
Animals
Armin - pharmacology
In Vitro Techniques
Membrane Potentials - drug effects
Organophosphorus Compounds - pharmacology
Rana temporaria
Ranvier's Nodes - drug effects
Ranvier's Nodes - physiology
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Summary:Study of the action of armin on the nodes of Ranvier in isolated nerve fibers of the frog has demonstrated that armin at concentrations over 4 X 10(-7) M produces the growth of the input resistance of the nodes of Ranvier at the expense of the decreased leakage conduction. At concentrations of 4 X 10(-6) and 4 X 10(-5) armin leads to a shift of the firing level of action potentials towards more positive values.
ISSN:0365-9615