Male depression--stress reaction combined with serotonin deficiency?

An educational programme on depressive disorders, given to general practitioners on the Swedish island of Gotland, resulted in a statistically significant reduction of the suicide rate among women, though that among men was virtually unaffected. Further analysis showed the profile of depression amon...

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Bibliographic Details
Published inLäkartidningen Vol. 96; no. 10; p. 1177
Main Authors Rutz, W, Wålinder, J, Rhimer, Z, Pestality, P
Format Journal Article
LanguageSwedish
Published Sweden 10.03.1999
Subjects
Aggression
Depression - blood
Depression - diagnosis
Depression - etiology
Depressive Disorder - blood
Depressive Disorder - diagnosis
Depressive Disorder - etiology
Education, Medical, Continuing
Family Practice - education
Female
Humans
Male
Serotonin - deficiency
Sex Factors
Stress, Psychological - complications
Substance-Related Disorders - complications
Suicide - prevention & control
Suicide - psychology
Sweden
Sweden
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Summary:An educational programme on depressive disorders, given to general practitioners on the Swedish island of Gotland, resulted in a statistically significant reduction of the suicide rate among women, though that among men was virtually unaffected. Further analysis showed the profile of depression among men to differ from that among women, the male pattern typically being more characterised by irritability, aggressiveness, acting out, antisocial behaviour and alcohol abuse, and reduced impulse control and stress tolerance. Predisposition to affective disorders, suicide and alcoholism seems to be genetically determined. The syndrome, which is not easily recognised and is seldom properly treated or prevented, seems to be related to central serotonin deficiency and hypercortisolaemia.
ISSN:0023-7205