Translate the untranslated: excising as a novel post-splicing event

• Published in: bioRxiv
• Main Authors: Panteleev, Dmitry Y, Reshetnikov, Roman V, Samoylenkova, Nadezhda S, Pustogarov, Nikolay A, Pavlova, Galina V
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 07.02.2020
• Subjects: 3' Untranslated regions; Alternative splicing; Clonal deletion; Cloning vectors; Polyadenylation; Post-transcription; RNA editing; RNA processing; RNA-binding protein; Structure-function relationships

Maturing of a messenger RNA (mRNA) is a multi-way process producing mRNA variants through diverse splicing events, alternative polyadenylation, RNA editing, etc. Studying post-transcriptional processing of human cold-inducible RNA binding protein (CIRBP), we discovered yet another mechanism that cou...