Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems

• Published in: bioRxiv
• Main Authors: Ghammraoui, Bahaa, Taguchi, Katsuyuki, Glick, Stephen J
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 10.06.2022
• Subjects: Acidity; Breast; Gallium; Gallium arsenide; Mammography; Sensors; Sodium channels; Software; Validation studies; X-rays
• DOI: 10.1101/2022.06.10.495610

We present an upgraded version of the Photon Counting Toolkit (PcTK), a publicly available MATLAB tool for the simulation of semiconductor-based photon counting detectors (PCD), which has been extended and validated to account for gallium arsenide (GaAs)-based PCD(s). The modified PcTK version was validated by performing simulations and acquiring experimental data for three different cases. The LAMBDA 60 K module planar detector (X-Spectrum GmbH, Germany) based on the Medipix3 ASIC technology was used in all cases. This detector has a 500-μm thick GaAs sensor and a 256 × 256-pixel array 55 μm pixel size. The first validation was a comparison between simulated and measured spectra from a 109 Cd radionuclide source. In the second validation study, experiments and simulations of mammography spectra were conducted to observe the performance of the GaAs version of the PcTK with polychromatic radiation used in conventional x-ray imaging systems. The third validation study used single event analysis to validate the spatio-energetic model of the extended PcTK version. Overall, the software provided a good agreement between simulated and experimental data, validating the accuracy of the GaAs model. The software could be an attractive tool for accurate simulation of breast imaging modalities relying on photon counting detectors and therefore could assist in their characterization and optimization. Competing Interest Statement The authors have declared no competing interest.