Brain monoaminergic activity during predator inspection in the Trinidadian guppy (Poecilia reticulata)

• Published in: bioRxiv
• Main Authors: Dimitriadou, Sylvia, Winberg, Svante, Per-Ove Thörnqvist, Croft, Darren P, Darden, Safi K
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 25.11.2021
• Subjects: Decision making; Dopamine receptors; Monoamines; Neurotransmission; Neurotransmitters; Poecilia reticulata; Serotonin; Social environment
• DOI: 10.1101/2021.11.25.469990

To understand the processes underpinning social decision-making, we need to determine how internal states respond to information gathered from the social environment. Brain monoamine neurotransmitters are key in the appraisal of the social environment and can reflect the internal state underlying behavioural responses to social stimuli. Here we determined the effects of conspecific partner cooperativeness during predator inspection on brain monoamine metabolic activity in Trinidadian guppies (Poecilia reticulata). We quantified the concentration of dopamine, serotonin and their metabolites across brain sections sampled immediately after ostensibly experiencing cooperation or defection from social partners whilst inspecting a predator model. Our results indicate dopaminergic and serotonergic activity differs with the cooperativeness experienced; these different neurotransmission profiles are likely to affect the expression and regulation of downstream behaviours that ultimately contribute to the patterning of cooperative interactions among individuals in the population. Competing Interest Statement The authors have declared no competing interest.