PHYTOCHEMICAL, ANTIOXIDANT ACTIVITY AND CYTOTOXICITY OF METHANOLIC EXTRACT OF Balanites aegyptiaca (L.) DELILE
Balanites aegyptiaca (L.) Del. belongs to family balanitaceae. The bark, unripe, fruits, and leaves of this plant are reported to have anthelminthic, antifertility, purgative and antidysenteric Properties. The present study was conducted to investigate the in-vitro antioxidant (DPPH assay), cytotoxi...
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Published in | Pharmacie Globale : International Journal of Comprehensive Pharmacy Vol. 7; no. 1; p. 1 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Roorkee
Pharmacie Globale
01.01.2016
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Abstract | Balanites aegyptiaca (L.) Del. belongs to family balanitaceae. The bark, unripe, fruits, and leaves of this plant are reported to have anthelminthic, antifertility, purgative and antidysenteric Properties. The present study was conducted to investigate the in-vitro antioxidant (DPPH assay), cytotoxic (MTT assay) and phytocemical of methanol extract of B. aegyptiaca (leaves). Antioxidant activity of the methanol extract of B. aegyptiaca (leaves) was screened for its free radical scavenging properties using 2.2Di-(4-tert-octylphenyl)-1-picryl-hydrazyl (DPPH), while propyl galate was used as standard antioxidant and screened for their cytotoxicity using 3- (4, 5dimethyl thiazol-2-yl)-2, 5- diphenyl tetrazolium bromide (MTT). The tested antioxidant activity gave (70 ± 0.07 RSA%) in comparison to the control of propylgalate levels (88 ± 0.07 RSA%), MTT assay verified the safety of the examined extract. The results of Phytochemical screening of B. aegyptiaca (leaves) showed that positive results were recorded for terpenoids, alkaloids, saponins and coumarins. Negative results were flavonoids, anthraquinone and tannins. |
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AbstractList | Balanites aegyptiaca (L.) Del. belongs to family balanitaceae. The bark, unripe, fruits, and leaves of this plant are reported to have anthelminthic, antifertility, purgative and antidysenteric Properties. The present study was conducted to investigate the in-vitro antioxidant (DPPH assay), cytotoxic (MTT assay) and phytocemical of methanol extract of B. aegyptiaca (leaves). Antioxidant activity of the methanol extract of B. aegyptiaca (leaves) was screened for its free radical scavenging properties using 2.2Di-(4-tert-octylphenyl)-1-picryl-hydrazyl (DPPH), while propyl galate was used as standard antioxidant and screened for their cytotoxicity using 3- (4, 5dimethyl thiazol-2-yl)-2, 5- diphenyl tetrazolium bromide (MTT). The tested antioxidant activity gave (70 ± 0.07 RSA%) in comparison to the control of propylgalate levels (88 ± 0.07 RSA%), MTT assay verified the safety of the examined extract. The results of Phytochemical screening of B. aegyptiaca (leaves) showed that positive results were recorded for terpenoids, alkaloids, saponins and coumarins. Negative results were flavonoids, anthraquinone and tannins. Balanites aegyptiaca (L.) Del. belongs to family balanitaceae. The bark, unripe, fruits, and leaves of this plant are reported to have anthelminthic, antifertility, purgative and antidysenteric Properties. The present study was conducted to investigate the in-vitro antioxidant (DPPH assay), cytotoxic (MTT assay) and phytocemical of methanol extract of B. aegyptiaca (leaves). Antioxidant activity of the methanol extract of B. aegyptiaca (leaves) was screened for its free radical scavenging properties using 2.2Di-(4-tert-octylphenyl)-1-picryl-hydrazyl (DPPH), while propyl galate was used as standard antioxidant and screened for their cytotoxicity using 3- (4, 5dimethyl thiazol-2-yl)-2, 5- diphenyl tetrazolium bromide (MTT). The tested antioxidant activity gave (70 plus or minus 0.07 RSA%) in comparison to the control of propylgalate levels (88 plus or minus 0.07 RSA%), MTT assay verified the safety of the examined extract. The results of Phytochemical screening of B. aegyptiaca (leaves) showed that positive results were recorded for terpenoids, alkaloids, saponins and coumarins. Negative results were flavonoids, anthraquinone and tannins. |
Author | Ibrahim, Elwaleed E |
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Title | PHYTOCHEMICAL, ANTIOXIDANT ACTIVITY AND CYTOTOXICITY OF METHANOLIC EXTRACT OF Balanites aegyptiaca (L.) DELILE |
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