PHYTOCHEMICAL, ANTIOXIDANT ACTIVITY AND CYTOTOXICITY OF METHANOLIC EXTRACT OF Balanites aegyptiaca (L.) DELILE

• Published in: Pharmacie Globale : International Journal of Comprehensive Pharmacy Vol. 7; no. 1; p. 1
• Main Author: Ibrahim, Elwaleed E
• Format: Journal Article
• Language: English
• Published: Roorkee Pharmacie Globale 01.01.2016
• ISSN: 0976-8157; 0976-8157

Balanites aegyptiaca (L.) Del. belongs to family balanitaceae. The bark, unripe, fruits, and leaves of this plant are reported to have anthelminthic, antifertility, purgative and antidysenteric Properties. The present study was conducted to investigate the in-vitro antioxidant (DPPH assay), cytotoxic (MTT assay) and phytocemical of methanol extract of B. aegyptiaca (leaves). Antioxidant activity of the methanol extract of B. aegyptiaca (leaves) was screened for its free radical scavenging properties using 2.2Di-(4-tert-octylphenyl)-1-picryl-hydrazyl (DPPH), while propyl galate was used as standard antioxidant and screened for their cytotoxicity using 3- (4, 5dimethyl thiazol-2-yl)-2, 5- diphenyl tetrazolium bromide (MTT). The tested antioxidant activity gave (70 ± 0.07 RSA%) in comparison to the control of propylgalate levels (88 ± 0.07 RSA%), MTT assay verified the safety of the examined extract. The results of Phytochemical screening of B. aegyptiaca (leaves) showed that positive results were recorded for terpenoids, alkaloids, saponins and coumarins. Negative results were flavonoids, anthraquinone and tannins.