COMPARATIVE EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF SOFT CORALS COLLECTED FROM THE WATER OF PANGGANG ISLAND, KEPULAUAN SERIBU

The need for new antibiotic compounds to overcome the resistance of pathogenic bacteria on existing antibiotics is increasing at this time. Softcorals are a rich source of bioactive compounds, have biological activity such as antifungal, cytotoxic, antimicrobial, antiinflammatory, etc. This study ev...

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Published inPharmacie Globale : International Journal of Comprehensive Pharmacy Vol. 3; no. 6; p. 1
Main Authors Setyaningsih, Iriani, Nurhayati, Tati, Nugraha, Roni, Gunawan, Indra
Format Journal Article
LanguageEnglish
Published Roorkee Pharmacie Globale 01.06.2012
Subjects
Aeromonas hydrophila
Dendronephthya
Escherichia coli
Nephthea
Pseudomonas aeruginosa
Sarcophyton
Sinularia
Vibrio harveyi
Xenia
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Summary:The need for new antibiotic compounds to overcome the resistance of pathogenic bacteria on existing antibiotics is increasing at this time. Softcorals are a rich source of bioactive compounds, have biological activity such as antifungal, cytotoxic, antimicrobial, antiinflammatory, etc. This study evaluated antibacterial activity of softcorals collected from the waters of Panggang Island, Kepulauan Seribu. Five collected softcorals, namely Sinularia sp., Sarcophyton sp., Xenia sp., Dendronephthya sp., and Nephthea sp. were extracted with the methanol, ethyl acetate and hexane. Antibacterial activity of softcorals was determined by disc diffusion method against Escherichia coli, Pseudomonas aeruginosa, Aeromonas hydrophila, and Vibrio harveyi. The result showed that extract of softcorals exhibited antibacterial activity on one or more tested bacteria. Softcoral Sinularia sp. produced the highest inhibitory zone, while Xenia sp and Sarchopyton sp. produced the weakest antibacterial activity. Methanol extracts had the highest antibacterial activity on all tested softcorals, with maximum activity against Vibrio harveyi. The results of this study indicate that the methanol extract of the softcoral Sinularia sp. has potential as a source of antibacterial compounds.
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ISSN:0976-8157
0976-8157