A System for Rapid DNA Sequencing with Flourescent Chain-Terminating Dideoxynucleotides

A DNA sequencing system based on the use of a set of four chain-terminating dideoxynucleotides, each carrying a different chemically tuned succinylflourescien dye distinguished by its flourescent emission is described.

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 238; no. 4825; p. 336
Main Authors Prober, James M, Trainor, George L, Dam, Rudy J, Hobbs, Frank W, Robertson, Charles W
Format Journal Article
LanguageEnglish
Published Washington The American Association for the Advancement of Science 16.10.1987
Subjects
Biotechnology
Genetics
Medical research
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Summary:A DNA sequencing system based on the use of a set of four chain-terminating dideoxynucleotides, each carrying a different chemically tuned succinylflourescien dye distinguished by its flourescent emission is described.
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ISSN:0036-8075
1095-9203