Temperature dependence of cloned mammalian and salmonid cardiac Na+/Ca2+ exchanger isoforms
The cardiac Na+/Ca(2+) exchanger (NCX), an important regulator of cytosolic Ca(2+) concentration in contraction and relaxation, has been shown in trout heart sarcolemmal vesicles to have high activity at 7degreesC relative to its mammalian isoform. This unique property is likely due to differences i...
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Published in | American Journal of Physiology: Cell Physiology Vol. 50; no. 3; pp. C993 - C1000 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Bethesda, MD
American Physiological Society
01.09.2001
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Subjects | |
Online Access | Get full text |
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Summary: | The cardiac Na+/Ca(2+) exchanger (NCX), an important regulator of cytosolic Ca(2+) concentration in contraction and relaxation, has been shown in trout heart sarcolemmal vesicles to have high activity at 7degreesC relative to its mammalian isoform. This unique property is likely due to differences in protein structure. |
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ISSN: | 0363-6143 1522-1563 |