Natriuretic peptide receptor-B in adult rat ventricle is predominantly confined to the nonmyocyte population

We assessed the cellular localizaiton and relative concentration of the C-type natruretic peptide (CnP) guanylate cyclase-B (GC-B) receptor in the adult rat heart ventricle by several techniques. In frozen sections of the ventricle, anti-receptor antibody stained the vasculature and cells intersitit...

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Bibliographic Details
Published inAmerican journal of physiology. Heart and circulatory physiology Vol. 51; no. 6; pp. H2117 - H2123
Main Authors DOYLE, Donald D, UPSHAW-EARLEY, Judy, BELL, Eric L, PALFREY, H. Clive
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.06.2002
Subjects
Biological and medical sciences
Circulatory system
Fundamental and applied biological sciences. Psychology
Heart
Peptides
Rodents
Vertebrates: cardiovascular system
Heart
Rat
Enzyme
Rodentia
Phosphorus-oxygen lyases
Smooth muscle
Heart ventricle
Lyases
Gene expression
Guanylate cyclase
C type natriuretic peptide
Vertebrata
Mammalia
Adult animal
Peptidergic receptor
Circulatory system
Localization
Fibroblast
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Summary:We assessed the cellular localizaiton and relative concentration of the C-type natruretic peptide (CnP) guanylate cyclase-B (GC-B) receptor in the adult rat heart ventricle by several techniques. In frozen sections of the ventricle, anti-receptor antibody stained the vasculature and cells intersititial to myocytes, but not the myocytes themselves.
ISSN:0363-6135
1522-1539