Regulation of SP-B and SP-C secretion in rat type II cells in primary culture

Secretion of lung surfactant phospholipids is a highly regulated process. A variety of physiological and pharmacological agents stimulate surfactant phospholipid secretion in isolated type II cells.

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Bibliographic Details
Published inAmerican journal of physiology. Lung cellular and molecular physiology Vol. 25; no. 6; pp. L1413 - L1419
Main Authors GOBRAN, Laurice I, ROONEY, Seamus A
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.12.2001
Subjects
Air breathing
Biological and medical sciences
Cells
Fundamental and applied biological sciences. Psychology
Lungs
Proteins
Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics
Rodents
Vertebrates: respiratory system
Alveolar type II cell
Agonist
Rat
Lung
Rodentia
Phospholipid
Hydrophobic compound
Respiratory system
In vitro
Protein
Vertebrata
Regulation(control)
Mammalia
Pulmonary surfactant
P2Y2 purinergic receptor
Animal
Primary culture
Exocrine secretion
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Summary:Secretion of lung surfactant phospholipids is a highly regulated process. A variety of physiological and pharmacological agents stimulate surfactant phospholipid secretion in isolated type II cells.
ISSN:1040-0605
1522-1504