The influence of topical capsaicin on the local thermal control of skin blood flow in humans

To test whether heat-sensitive receptors participate in the cutaneous vascular responses to direct heating, we monitored skin blood flow (SkBF; laser Doppler flowmetry) where the sensation of heat was induced either by local warming (TLOC; Peltier cooling/heating unit) or by both direct warming and...

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Published inAmerican journal of physiology. Regulatory, integrative and comparative physiology Vol. 50; no. 3; pp. R894 - R901
Main Authors STEPHENS, Dan P, CHARKOUDIAN, Nisha, BENEVENTO, Jessica M, JOHNSON, John M, SAUMET, Jean Louis
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.09.2001
Subjects
Biological and medical sciences
Circulatory system
Fundamental and applied biological sciences. Psychology
Heat
Sensory perception
Skin
Temperature
Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue
Human
Regional blood flow
Noxious stimulus
Vasomotricity
Heat
Nociceptor
Temperature
Capsaicin
Thermal stimulus
Skin
Hemodynamics
Vasodilation
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Summary:To test whether heat-sensitive receptors participate in the cutaneous vascular responses to direct heating, we monitored skin blood flow (SkBF; laser Doppler flowmetry) where the sensation of heat was induced either by local warming (TLOC; Peltier cooling/heating unit) or by both direct warming and chemical stimulation of heat-sensitive nociceptors (capsaicin).
ISSN:0363-6119
1522-1490