Three-dimensional multi-component analysis of Aurantii Fructus quality and research on influencing factors

• Published in: Zhongguo zhongyao zazhi Vol. 48; no. 1; p. 265
• Main Authors: Liu, Zi-Xuan, Fu, Xue-Sen, Wang, Ling, Liu, Xiang-Dan, Zhou, Ri-Bao
• Format: Journal Article
• Language: Chinese
• Published: China 01.01.2023
• Subjects: Chromatography, High Pressure Liquid - methods; Citrus; Coumarins - analysis; Drugs, Chinese Herbal; Flavonoids - analysis; Fruit - chemistry; quality evaluation; Aurantii Fructus; indicator components; three-dimensional multi-component
• ISSN: 1001-5302
• DOI: 10.19540/j.cnki.cjcmm.20221015.101

The present study explored the consistency of the content proportions of active components of Aurantii Fructus and analyzed the influencing factors based on three-dimensional multi-component analysis. A total of 839 Aurantii Fructus samples in 65 research articles were analyzed using the three-dimensional multi-component analysis mode. The content data of flavonoid components(naringin, hesperidin, neohesperidin, narirutin, and nobiletin), coumarin components(meranzin and gluconolactone), and alkaloid(synephrine) in 386 samples which met the criteria of 2020 edition of the Chinese Pharmacopoeia were extracted and adjusted to percentages, and the content ratios between components were calculated. The influencing factors of Aurantii Fructus quality were analyzed. The results showed content ratios of components as follows: neohesperidin∶naringin in the range of 0.4-1.2; narirutin∶naringin in the range of 0.02-0.16; hesperidin∶naringin in the range of 0.01-0.3; nobiletin∶naringin in the range of 0.000 588 3-0.069