Reflex vascular responses in the anesthetized dog to large rapid changes in carotid sinus pressure

This study examined reflex vascular responses to large rapid increases and decreases in carotid sinus pressure to determine whether delayed or inappropriate vascular responses might be obtained that, if they occurred in people, could lead to hypotension during exposure to rapidly alternating gravita...

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Published inAmerican journal of physiology. Heart and circulatory physiology Vol. 44; no. 4; pp. H1169 - H1177
Main Authors DOE, C. P. A, SELF, D. A, DRINKHILL, M. J, MCMAHON, N, MYERS, D. S, HAINSWORTH, R
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.10.1998
Subjects
Biological and medical sciences
Blood pressure
Coronary vessels
Dogs
Fundamental and applied biological sciences. Psychology
Heart
Hemodynamics. Rheology
Vertebrates: cardiovascular system
Fissipedia
Carnivora
Nervous system diseases
Consciousness impairment
Vasoconstriction
Artery
Vasodilation
Thoracic aorta
Vasomotricity
Vertebrata
Mammalia
Vascular resistance
Syncope
Blood vessel
Blood pressure
Circulatory system
Hemodynamics
Baroreceptor
Neurological disorder
Dog
Carotid sinus
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Summary:This study examined reflex vascular responses to large rapid increases and decreases in carotid sinus pressure to determine whether delayed or inappropriate vascular responses might be obtained that, if they occurred in people, could lead to hypotension during exposure to rapidly alternating gravitational forces. In chloralose-anesthetized open-chest dogs, a perfusion circuit controlled carotid sinus and thoracic aortic pressures and blood flows to both the vascularly isolated abdominal circulation and a hindlimb (perfusion pressure changes denoted resistance).
ISSN:0363-6135
1522-1539