Respiratory infectious diseases and tissue "damage-repair" balance:pathological characteristics, treatment, and characteristics of traditional Chinese medicine

• Published in: Zhongguo zhongyao zazhi Vol. 46; no. 24; p. 6366
• Main Authors: Yang, Man-Li, DU, Xin-Ke, Kan, Xiao-Xi, Hao, Teng-Teng, Ran, Qing-Sen
• Format: Journal Article
• Language: Chinese
• Published: China 01.12.2021
• Subjects: Drugs, Chinese Herbal - therapeutic use; Humans; Medicine, Chinese Traditional; Respiratory Tract Infections - therapy; "damage-repair" balance; traditional Chinese medicine treatment; host-directed therapies; respiratory infectious diseases
• ISSN: 1001-5302
• DOI: 10.19540/j.cnki.cjcmm.20211009.601

Respiratory infectious diseases are important diseases causing major public safety events, posing a great threat to life, health, and social development. Effective control and scientific treatment of the diseases is the key basis for ensuring the stability and long-term development of the community of a shared future for human health. Although the pathogens of respiratory viral infectious diseases are diverse and the process is complex, the common pathological basis of their pathogenesis is characterized by the "damage-repair" functional imbalance of the immune microenvironment of the lesions, which leads to the subsequent structural and functional destruction of important organs. Therefore, the treatment should focus on antivirus and immunological regulation, strengthen the protection against immune injury, and promote the functional repair of damaged tissues. The above conclusions are the scientific core of host-directed therapies(HDT), which coincides with "human-disease co-treatment and healthy qi and pat