ACE inhibition and ANG II receptor blockade improve glomerular size-selectivity in IgA nephropathy
Protein trafficking across the glomerular capillary has a pathogenic role in subsequent renal damage. Despite evidence that angiotensin-converting enzyme (ACE) inhibitors improve glomerular size-selectivity, whether this effect is solely due to ANG II blocking or if other mediators also play a contr...
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Published in | American journal of physiology. Renal physiology Vol. 45; no. 3; pp. F457 - FF466 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Bethesda, MD
American Physiological Society
01.03.1999
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Subjects | |
Online Access | Get full text |
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Summary: | Protein trafficking across the glomerular capillary has a pathogenic role in subsequent renal damage. Despite evidence that angiotensin-converting enzyme (ACE) inhibitors improve glomerular size-selectivity, whether this effect is solely due to ANG II blocking or if other mediators also play a contributory role is not clear yet. |
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ISSN: | 1931-857X 1522-1466 |