ACE inhibition and ANG II receptor blockade improve glomerular size-selectivity in IgA nephropathy

Protein trafficking across the glomerular capillary has a pathogenic role in subsequent renal damage. Despite evidence that angiotensin-converting enzyme (ACE) inhibitors improve glomerular size-selectivity, whether this effect is solely due to ANG II blocking or if other mediators also play a contr...

Full description

Saved in:
Bibliographic Details
Published inAmerican journal of physiology. Renal physiology Vol. 45; no. 3; pp. F457 - FF466
Main Authors REMUZZI, A, PERICO, N, SANGALLI, F, VENDRAMIN, G, MORIGGI, M, RUGGENENTI, P, REMUZZI, G
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.03.1999
Subjects
Anatomy & physiology
Antihypertensive agents
Biological and medical sciences
Cardiovascular system
Kidneys
Medical sciences
Pharmacology. Drug treatments
Kidney disease
Human
Glomerulonephritis
Immunopathology
IgA
Urinary system disease
Glomerular filtration
Renal function
Selectivity
Molecular size
Clearance
Kidney
Urinary system
Enalapril
Irbesartan
Peptidergic receptor
Blood pressure
Hemodynamics
Angiotensin antagonist
ACE inhibitor
Proteinuria
Online AccessGet full text

Cover

More Information
Summary:Protein trafficking across the glomerular capillary has a pathogenic role in subsequent renal damage. Despite evidence that angiotensin-converting enzyme (ACE) inhibitors improve glomerular size-selectivity, whether this effect is solely due to ANG II blocking or if other mediators also play a contributory role is not clear yet.
ISSN:1931-857X
1522-1466