OPISTHORCHIASIS AS A PROMOTER OF GASTRIC CARCINOGENESIS

The paper presents an experimental model of gastric cancer in the presence of chronic opisthorchiasis, which has been created to study its possible role in gastric carcinogenesis. The performed investigation has supported the hypothesis that opisthorchiasis plays a promoting role in the development...

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Published inMeditsinskaia parazitologiia i parazitarnye bolezni no. 4; p. 7
Main Authors Zuevsky, V P, Bychkov, V G, Tselishcheva, P V, Khadieva, E D
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.10.2015
Subjects
Animals
Carcinogenesis - chemically induced
Carcinogenesis - pathology
Cricetinae
Disease Models, Animal
Fishes - parasitology
Humans
Mesocricetus
Methylnitronitrosoguanidine - toxicity
Opisthorchiasis - complications
Opisthorchiasis - parasitology
Opisthorchiasis - pathology
Stomach Neoplasms - chemically induced
Stomach Neoplasms - etiology
Stomach Neoplasms - pathology
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Summary:The paper presents an experimental model of gastric cancer in the presence of chronic opisthorchiasis, which has been created to study its possible role in gastric carcinogenesis. The performed investigation has supported the hypothesis that opisthorchiasis plays a promoting role in the development of experimental gastric cancer. A larger number of experimental hamsters receiving the carcinogen methylnitronitrosoguanidine (MNNG) developed earlier gastric tumors in. the presence of chronic opisthorchiasis than the control animals in the experiment.
ISSN:0025-8326