Contents and isomers distribution of vitamin E in human mature breast milk from six regions of China in 2018-2019

• Published in: Wei sheng yan jiu Vol. 50; no. 6; p. 914
• Main Authors: Lou, Zeru, Wu, Ke, Xu, Yizi, Cai, Xiaokun, Tian, Fang, Mao, Yingyi, Zhao, Yanrong, Cai, Meiqin
• Format: Journal Article
• Language: Chinese
• Published: China 01.11.2021
• Subjects: alpha-Tocopherol - analysis; China; Female; Humans; Lactation; Milk, Human - chemistry; Stereoisomerism; Vitamin E; China; mature breast milk; RRR-α-tocopherol; vitamin E; α-tocopherol
• ISSN: 1000-8020
• DOI: 10.19813/j.cnki.weishengyanjiu.2021.06.007

The study aimed to investigate the contents and isomer composition of vitamin E in mature milk in different regions of China. Simultaneously recruited 604 lactating mothers aged(29.58±3.43) from Shanghai, Guangzhou, Tianjin, Chengdu, Lanzhou and Changchun cities. They were mainly primiparas with good education background. A total number of 604 mature milk samples was collected. The contents of α-, γ-, δ-tocopherols and the stereoisomers of α-tocopherol were determined by high performance liquid chromatography(HPLC). The M(P25, P75) concentrations of α-tocopherol, RRR-α-tocopherol, γ-tocopherol and δ-tocopherol in Chinese mature milk were 3.16(2.29, 4.16)mg/L, 2.57(1.77, 3.48)mg/L, 0.89(0.58, 1.27)mg/L and 0.17(0.09, 0.27)mg/L, respectively. The total α-TE level was 3.09(2.22, 4.10)mg/L with statistically regional differences(P<0.001). RRR-α-tocopherol was the predominated stereoisomers of α-tocopherol, accounting for 83.17%(76.36%, 88.43%). The proportion of RRR in Tianjin mature milk was significantly lower