Association of erectile dysfunction with hypogonadism and metabolic syndrome among men of various age groups

• Published in: Advances in gerontology = Uspekhi gerontologii Vol. 25; no. 4; p. 685
• Main Authors: Novikova, E G, Lutov, Iu V, Seliatitskaia, V G
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2012
• Subjects: Adult; Aging - blood; Data Interpretation, Statistical; Erectile Dysfunction - complications; Erectile Dysfunction - diagnosis; Erectile Dysfunction - epidemiology; Eunuchism - complications; Eunuchism - diagnosis; Eunuchism - epidemiology; Humans; Male; Metabolic Syndrome - complications; Metabolic Syndrome - diagnosis; Metabolic Syndrome - epidemiology; Middle Aged; Severity of Illness Index; Testosterone - blood; Young Adult
• ISSN: 1561-9125

The integrated study included 184 men aged from 22 to 60 years who were formed into two groups, of the first and second period of middle age. The direct relation of both erectile dysfunction frequency and expressiveness from age was developed. The same dependence was found for hypogonadism clinical features, metabolic syndrome and its components, but inverse relation was detected between age and testosterone content in blood. The presence of erectile dysfunction was associated with testosterone level reduction, hypogonadism clinical features frequency, metabolic syndrome and most its components increase without the age. It was shown that first and second period of middle age men with erectile dysfunction did not display the difference in blood testosterone content, metabolic syndrome and its components frequency. Hence, the main risk factors of erectile dysfunction development form qualitatively already in young men; they accumulate quantitatively with age producing the androgenous disorders evolution.