Initiating Standardization in Fish Embryo Toxicity Assays

Aquatic ecotoxicology, like ecotoxicology lato sensu, is a dynamic research field, based on laboratory experiments or field investigations and data collection. Such a research branch is important because it helps us understanding the level of toxicity of various chemical compounds used or proposed f...

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Bibliographic Details
Published inProenvironment Vol. 8; no. 24
Main Authors Alămorean, Ștefania, Albu, Cristian, Cioban, Roxana, Miclăuș, Mădălina, Suciu, Vasilena, Camelia FiruÅ£a Oroian, Petrescu-Mag, Ioan Valentin
Format Journal Article
LanguageEnglish
Published Cluj-Napoca Bioflux SRL 01.01.2015
Subjects
Agrochemicals
Assaying
Chemical compounds
Data collection
Ecotoxicology
Field tests
Fish
Literature reviews
Species
Standardization
Toxicity
Zebrafish
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Summary:Aquatic ecotoxicology, like ecotoxicology lato sensu, is a dynamic research field, based on laboratory experiments or field investigations and data collection. Such a research branch is important because it helps us understanding the level of toxicity of various chemical compounds used or proposed for use in agriculture and industry. After a review of the literature, we summarized in this paper the most recent trends in fish embryo toxicity assays. In the past, each researcher considered his own reasons to design the experimental protocol and chose the study animals. At present, these assays seem to harmonize under different but common standards elaborated by OECD, USEPA etc and, thus, common reference levels/values for studied chemicals are now available, making different results to be comparable and reproducible. OECD put the basis of embryo toxicity tests in three small fish species: zebrafish, Japanese medaka, and fathead minnow. Although there are many other fish species which demonstrated to be good models for research, the species number was limited to three in order to concentrate the information and standardize the protocols. Low number of model species and low number of protocols both mean high number of similar experiments which are comparable each other, and all these are comparable with OECD standard values.
ISSN:1844-6698
2066-1363