Analysis of management efficacy in patients with heavy menstrual bleeding associated with antithrombotic therapy

• Published in: Chung-hua fu chʿan kʿo tsa chih Vol. 58; no. 4; p. 286
• Main Authors: Jiang, X L, Yan, X, Su, H N, Liu, Y H, Han, R X, Song, Z Y, Sun, X W, Su, D H, Yang, X
• Format: Journal Article
• Language: Chinese
• Published: China 25.04.2023
• Subjects: Adult; Amenorrhea - drug therapy; Contraceptive Agents, Female; Female; Fibrinolytic Agents - adverse effects; Hemoglobins; Humans; Intrauterine Devices, Medicated - adverse effects; Levonorgestrel - adverse effects; Menorrhagia - drug therapy; Menorrhagia - etiology; Mifepristone - therapeutic use; Quality of Life; Rivaroxaban - therapeutic use
• ISSN: 0529-567X
• DOI: 10.3760/cma.j.cn112141-20221130-00725

To evaluate different methods' efficacy of controlling acute bleeding and managing long-term menstruation in patients with heavy menstrual bleeding (HMB) associated with antithrombotic therapy. The clinical data of 22 cases with HMB associated with antithrombotic therapy admitted to Peking University People's Hospital from January 2010 to August 2022 were analyzed, aged 39 years old (26-46 years). Changes in menstrual volume, hemoglobin (Hb), and quality of life were collected after control of acute bleeding and long-term menstrual management. Menstrual volume was assessed by pictorial blood assessment chart (PBAC), and quality of life was assessed by menorrhagia multi-attribute scale (MMAS). (1) Treatment of acute bleeding: of the 22 cases with HMB associated with antithrombotic therapy, 16 cases were treated in our hospital and 6 in other hospital for emergency bleeding; of the 16 cases treated in our hospital, 3 underwent emergency intrauterine Foley catheter balloon compression due to severe bleeding (Hb