ANALYSIS AND COMPARISON OF SERUM LIPID PROFILE IN PATIENTS WITH DIABETIC MELLITUS AND HYPERTENSION IN A TERTIARY HEALTH CENTRE IN NORTH WEST NIGERIA

• Published in: West African journal of medicine Vol. 40; no. 12 Suppl 1; p. S14
• Main Authors: Isah, Idris Ainavi, Muhammad, Manko, Danimoh, Mustapha
• Format: Journal Article
• Language: French
• Published: Nigeria 04.12.2023
• ISSN: 0189-160X

Serum Lipid profile is an important biochemical parameter that can be used as a marker of adverse cardiovascular events. This study aim to analyze and compare serum lipid profile among hypertensive and diabetic patients. Serum lipid profile of 172 and 142 patients with diagnosis of hypertension and diabetes mellitus respectively seen over a 4year period were retrieved from the electronic data base of chemical pathology department of Barau Dikko Teaching Hopital, Kaduna. Percentages of patients with abnormal lipid values were calculated for the various lipids in the two groups of hypertension and diabetes and comparison of the mean was carried out in between the groups. Among hypertensives; 16.0%, 25.6%, 31.8% and 14.0% had abnormal HDL, LDL, total cholesterol and triglycerides respectively with 5.8% having both elevated cholesterol and triglyceride. In the diabetic group; 22.4%, 16.9%, 30.1% and 13.8% had abnormal HDL, LDL, total cholesterol and triglyceride respectively with 7.3% having both elevated total cholesterol and triglyceride. Comparison of mean of the various lipids among hypertensive and diabetic patients respectively is as follows: HDL (mean value 1.3±0.8 vs 1.2±0.3, t 1.737, p 0.08), LDL(mean value 3.3±1.0 vs 3.1±1.1, t 2.170, p 0.03), total cholesterol(mean value 5.3±1.2 vs 5.2±1.7, t 0.598, p 0.55) and triglyceride (mean value 1.6±1.0 vs 1.6±0.6, t 0.389, p 0.70). In this study, the predominant abnormality of lipids among the patients in the two groups was total hypercholesterolaemia and hypertensive patients had significantly higher LDL levels when compared to that of diabetic patients.