Glymphatic System and Idiopathic Normal Pressure Hydrocephalus

The inflow channel of the glymphatic pathway is the basilar membrane formed by the pia matter and glial border membrane in the outermost layer of the artery. Cerebrospinal fluid from the subarachnoid space enters the brain parenchyma through this pathway, and its water component is pumped into the b...

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Bibliographic Details
Published inBrain and nerve = Shinkei kenkyū no shinpo Vol. 76; no. 2; p. 117
Main Author Ihara, Masafumi
Format Journal Article
LanguageJapanese
Published Japan 01.02.2024
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Summary:The inflow channel of the glymphatic pathway is the basilar membrane formed by the pia matter and glial border membrane in the outermost layer of the artery. Cerebrospinal fluid from the subarachnoid space enters the brain parenchyma through this pathway, and its water component is pumped into the brain parenchyma through aquaporin 4. One of the driving forces is vascular pulsation, and if this pathway becomes inoperative, cerebrospinal fluid loses its normal dynamics and contributes to idiopathic normal pressure hydrocephalus. Future research is needed to determine the extent of this contribution to the development of idiopathic normal pressure hydrocephalus.
ISSN:1881-6096
DOI:10.11477/mf.1416202572