Outcome of Pregnancy Related Acute Kidney Injury Observed in a Tertiary Care Hospital

• Published in: Mymensingh medical journal : MMJ Vol. 26; no. 3; p. 463
• Main Authors: Ahammed, S U, Chowdhury, A A, Roy, A S, Muqueet, M A, Rahman, M A, Kabir, M S, Rabbani, M G, Asadujjaman, M, Hossain, M B, Akhtaruzzaman, M, Das, S K, Khan, E H, Islam, M A, Hasan, M J, Talukder, R K, Ara, J, Barman, G C, Roy, P P, Saha, M K, Mondal, D
• Format: Journal Article
• Language: English
• Published: Bangladesh 01.07.2017
• Subjects: Acute Kidney Injury - complications; Acute Kidney Injury - therapy; Adult; Case-Control Studies; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Tertiary Care Centers; Young Adult
• ISSN: 1022-4742

This prospective case control study was carried out in Mymensingh Medical College Hospital (MMCH) from April 2011 to March 2012. The main objective of the study was to determine the short term maternal outcome of pregnancy related Acute Kidney Injury and to identify aetiological factors and to observe clinical features of pregnancy related Acute Kidney Injury. Total 60 pregnant women with AKI were included in the study as sample and equal (60) number of pregnant women with normal renal function was taken as control. Mean ages (±SD) of study and control group were observed 31.6±6.9 years and 25.5±4.7 years respectively. It was observed that most patients were from rural area with low income group. Most women were multiparous and presented in third trimester and postpartum period. Majority of the study subjects did not receive antenatal care at any stage of pregnancy. Fifty (86.7%) of the study subjects were oligo-anuric, forty-nine (81.7%) were edematous and fifty one (85%) were anaemic. Twenty-five (41.7%) patients presented with abnormal vaginal bleeding. Sepsis (including septic abortion and puerperal sepsis) was responsible for of Pregnancy Related AKI (PR-AKI) in more than two fifths of cases. Haemorrhage (APH & PPH combined) was the next common cause of Pregnancy Related AKI (PR-AKI). Toxemia of Pregnancy was responsible in one fourth of cases. Dialysis (HD & IPD combined) was required for two fifths of the patients. Rest patients were treated conservatively with antibiotics, blood transfusion, maintenance of fluid and electrolytes balance etc. Maternal outcome of Pregnancy related acute kidney injury was considered for the period of patient's hospital staying. 56.6% patients recovered completely, 15.0% patients recovered partially, 6.7% did not recover at the time of hospital discharge; while 21.7% died. So it can be concluded that, pregnancy related acute kidney injury is a critical condition, associated with worse prognosis.