Increased oxidative capacity does not protect skeletal muscle fibers from eccentric contraction-induced injury

Isometric electrical stimulation was delivered to rabbit dorsiflexor muscles at 10 Hz for 1 s on and 1 s off over 30 min, 5 days/wk for 3 wk to induce an increase in muscle oxidative capacity. Stimulation trained muscles as well as untrained muscles were then subjected to a 30-min eccentric exercise...

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Bibliographic Details
Published inAmerican journal of physiology. Regulatory, integrative and comparative physiology Vol. 43; no. 5; pp. R1300 - R1308
Main Authors PATEL, T. J, CUIZON, D, MATHIEU-COSTELLO, O, FRIDEN, J, LIEBER, R. L
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.05.1998
Subjects
Biological and medical sciences
Exercise
Fundamental and applied biological sciences. Psychology
Injuries
Metabolism
Muscular system
Oxidation
Striated muscle. Tendons
Vertebrates: osteoarticular system, musculoskeletal system
Vertebrata
Mammalia
Rabbit
Oxidation
Muscular fiber
Lesion
Lagomorpha
Striated muscle
Metabolism
Muscle contraction
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Summary:Isometric electrical stimulation was delivered to rabbit dorsiflexor muscles at 10 Hz for 1 s on and 1 s off over 30 min, 5 days/wk for 3 wk to induce an increase in muscle oxidative capacity. Stimulation trained muscles as well as untrained muscles were then subjected to a 30-min eccentric exercise bout to test whether increased oxidative capacity provided a protective effect against muscle injury.
ISSN:0363-6119
1522-1490