Methemoglobinemia as a result of acute accidental “poppres” poisoning – a case report

Recently we observe an increase in the number of intoxications due to xenobiotics that may induce acute methemoglobinemia. Our study showed a case of acute methemoglobinemia (MetHb 55..2%) in 25 – year old man. Clinical symptoms were caused by ingestion of “poppers” which was used by patient as “aph...

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Bibliographic Details
Published inPrzeglad lekarski Vol. 73; no. 8; p. 593
Main Authors Schetz, Daria, Waldman, Wojciech, Sein Anand, Jacek
Format Journal Article
LanguagePolish
Published Poland 2016
Subjects
Adult
Antidotes - therapeutic use
Aphrodisiacs - poisoning
Humans
Male
Methemoglobinemia - chemically induced
Methemoglobinemia - drug therapy
Methylene Blue - therapeutic use
Nitrites - poisoning
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Summary:Recently we observe an increase in the number of intoxications due to xenobiotics that may induce acute methemoglobinemia. Our study showed a case of acute methemoglobinemia (MetHb 55..2%) in 25 – year old man. Clinical symptoms were caused by ingestion of “poppers” which was used by patient as “aphrodisiac”. Summary: Conclusions: 1. Oral intake of alkyl nitrites, including isobutyl nitrite, is burdened with the risk of life-threatening methemoglobinemia . 2. In the case of poisonings running with normal pO2, reduced level of oxygen saturation, clinical signs of cyanosis does not react to oxygen therapy, and “chocolate” tinge of blood methemoglobinemia should be suspected. 3. In every case of MetHb the use of antidote, which is methylene blue, should be considered. 4. The severity of cyanosis correlates with the level of methemoglobin.
ISSN:0033-2240