Bronchoscopic intervention therapy for pulmonary mucormycosis with main bronchial occlusion: a case report

Pulmonary mucormycosis is one of the most common types of mucormycosis. Tracheobronchial pulmonary mucormycosis primarily affects the tracheobronchial tree, causing lesions that can invade the airway mucosa and muscular layer, damaging the cartilage. It is characterised by acute onset, rapid progres...

Full description

Saved in:
Bibliographic Details
Published inZhonghua jiehe he huxi zazhi Vol. 47; no. 6; p. 550
Main Authors Wu, X X, Wang, J, Jin, Y K, Lin, L, Qiu, X J, Zhang, J, Wang, T
Format Journal Article
LanguageChinese
Published China 12.06.2024
Subjects
Antifungal Agents - therapeutic use
Bronchoscopy - methods
Humans
Lung Diseases, Fungal - therapy
Male
Middle Aged
Mucormycosis - diagnosis
Mucormycosis - therapy
Online AccessGet more information

Cover

More Information
Summary:Pulmonary mucormycosis is one of the most common types of mucormycosis. Tracheobronchial pulmonary mucormycosis primarily affects the tracheobronchial tree, causing lesions that can invade the airway mucosa and muscular layer, damaging the cartilage. It is characterised by acute onset, rapid progression, and high mortality rate, making clinical treatment challenging. This article reports the diagnosis and treatment of a patient with pulmonary mucormycosis complicated by left main bronchus occlusion. In addition to systemic treatment, which consisted mainly of an intravenous injection of amphotericin B combined with an oral suspension of posaconazole, the patient underwent multiple bronchoscopic interventions, including local infusion of amphotericin B under endoscopy, balloon dilation and silicone stent placement. After four months of comprehensive treatment, the therapeutic effect was satisfactory. This report demonstrates that bronchoscopic intervention therapy plays an important role in the comprehensive t
ISSN:1001-0939
DOI:10.3760/cma.j.cn112147-20231124-00338