A case of severe inflammatory bowel disease triggered by vaccination with SARS-CoV-2 mRNA

A 64-year-old woman received a third dose of SARS-CoV-2 mRNA vaccine. On the next day, she developed fever, diarrhea, and abdominal pain and had bloody stools. Total colonoscopy revealed deep ulceration on the whole colon. She was treated with corticosteroid and infliximab and her symptoms improved....

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Published inNippon Shōkakibyō Gakkai zasshi Vol. 120; no. 4; p. 325
Main Authors Takahashi, Yasutaka, Shimodaira, Yosuke, Yoshida, Tatsuki, Tajika, Munehiko, Takahashi, So, Watanabe, Kenta, Fukuda, Sho, Koizumi, Shigeto, Matsuhashi, Tamotsu, Iijima, Katsunori
Format Journal Article
LanguageJapanese
Published Japan 2023
Subjects
Colitis, Ulcerative - diagnosis
COVID-19 - prevention & control
COVID-19 Vaccines - adverse effects
Female
Humans
Middle Aged
RNA, Messenger - therapeutic use
SARS-CoV-2
Vaccination
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Summary:A 64-year-old woman received a third dose of SARS-CoV-2 mRNA vaccine. On the next day, she developed fever, diarrhea, and abdominal pain and had bloody stools. Total colonoscopy revealed deep ulceration on the whole colon. She was treated with corticosteroid and infliximab and her symptoms improved. She was diagnosed with severe enteritis resembling ulcerative colitis triggered by SARS-CoV-2 mRNA vaccination.
ISSN:0446-6586
DOI:10.11405/nisshoshi.120.325