Sample size for the estimation of F-wave parameters in healthy volunteers and amyotrophic lateral sclerosis patients

The study aimed to investigate whether sample sizes of F-wave study differed according to different nerves, different F-wave parameters, and amyotrophic lateral sclerosis(ALS) patients or healthy subjects. The F-waves in the median, ulnar, tibial, and deep peroneal nerves of 55 amyotrophic lateral s...

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Published inZhong hua yi xue za zhi Vol. 97; no. 9; p. 670
Main Authors Fang, J, Cui, L Y, Liu, M S, Guan, Y Z, Ding, Q Y, Du, H, Li, B H, Wu, S
Format Journal Article
LanguageChinese
Published China 07.03.2017
Subjects
Amyotrophic Lateral Sclerosis
Healthy Volunteers
Humans
Knee
Median Nerve
Neural Conduction
Peroneal Nerve
Sample Size
Ulnar Nerve
Amplitude
Persistence
Amyotrophic lateral sclerosis
F-waves
Latency
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Summary:The study aimed to investigate whether sample sizes of F-wave study differed according to different nerves, different F-wave parameters, and amyotrophic lateral sclerosis(ALS) patients or healthy subjects. The F-waves in the median, ulnar, tibial, and deep peroneal nerves of 55 amyotrophic lateral sclerosis (ALS) patients and 52 healthy subjects were studied to assess the effect of sample size on the accuracy of measurements of the following F-wave parameters: F-wave minimum latency, maximum latency, mean latency, F-wave persistence, F-wave chronodispersion, mean and maximum F-wave amplitude. A hundred stimuli were used in F-wave study. The values obtained from 100 stimuli were considered "true" values and were compared with the corresponding values from smaller samples of 20, 40, 60 and 80 stimuli. F-wave parameters obtained from different sample sizes were compared between the ALS patients and the normal controls. Significant differences were not detected with samples above 60 stimuli for chronodispersion i
ISSN:0376-2491
DOI:10.3760/cma.j.issn.0376-2491.2017.09.007