Outcomes and complications after phacoemulsification in retinoblastoma patients with cataract after radiation treatment

• Published in: Archivos de la Sociedad Española de Oftalmología Vol. 92; no. 4; p. 160
• Main Authors: Velásquez-Aguilar, M, Matiz-Moreno, H, Amato-Almanza, M, Chen-López, C Y, Márquez-García, G, Ramírez-Ortiz, M A
• Format: Journal Article
• Language: English; Spanish
• Published: Spain 01.04.2017
• Subjects: Cataract - etiology; Cataract Extraction - adverse effects; Child; Child, Preschool; Female; Humans; Male; Phacoemulsification - adverse effects; Postoperative Complications - etiology; Radiation Injuries - etiology; Retinal Neoplasms - radiotherapy; Retinal Neoplasms - surgery; Retinoblastoma - radiotherapy; Retinoblastoma - surgery; Treatment Outcome; Cataract; Facoemulsificación; Alteraciones inducidas por radioterapia; Radiation-induced abnormalities; Phacoemulsification; Retinoblastoma; Catarata
• ISSN: 1989-7286
• DOI: 10.1016/j.oftal.2016.11.011

To describe the visual outcome and complications associated with phacoemulsification in patients with bilateral retinoblastoma (Rb), with lens opacification secondary to external beam radiotherapy. A descriptive study was performed on patients with Rb, treated in Federico Gomez Children's Hospital, Mexico, from January 1997 to August 2015, with external beam radiotherapy eye salvaging. Statistical analysis was performed using Stata 10. A total of 15 patients were included. The mean age at phacoemulsification was 7.5 years. Mean preoperative visual acuity was 1.0LogMAR (range 0.4-1.6), and the mean postoperative visual acuity was 0.7LogMAR (range 0.1-1.6). Twelve patients had visual improvement (P<.05). The visual acuity decreased in one patient with vitreous haemorrhage and secondary glaucoma, and 2 patients with exudative maculopathy secondary to radiation. Mean follow up was 46 months and not a single patient showed tumour re-activation. Cataract surgery produces a statistically significant improvement in visual acuity. These patients have increased risk for eye complications in the mid- and long-term. It is important to conduct a close follow up due to reactivation of tumour.