Influencing factors of mild cognitive impairment among the Chinese elderly: a meta-analysis

• Published in: Zhong hua yi xue za zhi Vol. 103; no. 17; p. 1340
• Main Authors: Zhang, Y F, Zhang, H X, Yang, J C, Qu, Y M, Jiang, Y, Li, J L
• Format: Journal Article
• Language: Chinese
• Published: China 09.05.2023
• Subjects: Aged; Cardiovascular Diseases; Cognitive Dysfunction - epidemiology; Dementia - psychology; Diabetes Mellitus; East Asian People; Humans; Hypertension; Male; Obesity; Overweight; Risk Factors; Sleep Initiation and Maintenance Disorders
• ISSN: 0376-2491
• DOI: 10.3760/cma.j.cn112137-20220819-01765

To conduct a meta-analysis on the influencing factors of mild cognitive impairment (MCI) in the Chinese elderly. The literature related to the influencing factors of MCI in Chinese elderly population was retrieved through CNKI, Wanfang, VIP, PubMed, Embase and Web of Science databases up to March 13, 2022. Stata17.0 software was used to calculate the combined risk ratio ( with the 95% confidence interval ( , test the heterogeneity, and assess the publication bias. A total of 2 450 articles were retrieved, and 49 articles met the inclusion criteria, including 5 cohort studies and 44 case-control studies. Meta-analysis results showed that male ( =0.778, 95% : 0.696-0.870, =73.1), education>6years ( =0.428, 95% : 0.374-0.490, =86.9) and regular exercise ( =0.496, 95% : 0.421-0.585, =81.5) were protective factors for MCI, while age≥70 years ( =2.431, 95% : 2.086-2.833, =79.3), family history of dementia ( =3.228, 95% : 2.140-4.867, =0.0), smoking ( =1.214, 95% : 1.098-1.342, =78.8), alcohol consumption ( =1.165,