Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr olds

We determined whether shortterm weight-lifting exercise increases the synthesis rate of the major contractile proteins, myosin heavy chain (MHC), actin, and mixed muscle proteins in nonfrail elders and younger women and men. Fractional synthesis rates of mixed, MHC, and actin proteins were determine...

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Bibliographic Details
Published inAmerican journal of physiology: endocrinology and metabolism Vol. 41; no. 4; pp. E620 - E626
Main Authors HASTEN, D. L, PAK-LODUCA, J, OBERT, K. A, YARASHESKI, K. E
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.04.2000
Subjects
Age
Biological and medical sciences
Exercise
Fundamental and applied biological sciences. Psychology
Muscular system
Proteins
Striated muscle. Tendons
Vertebrates: osteoarticular system, musculoskeletal system
Human
Physical exercise
Heavy peptide chain
Contractile protein
Biosynthesis
Metabolism
Striated muscle
Weightlifting
Protein synthesis
Aminoacid
Young adult
Myosin
Elderly
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Summary:We determined whether shortterm weight-lifting exercise increases the synthesis rate of the major contractile proteins, myosin heavy chain (MHC), actin, and mixed muscle proteins in nonfrail elders and younger women and men. Fractional synthesis rates of mixed, MHC, and actin proteins were determined in seven healthy sedentary 23- to 32-yr-old and seven healthy 78- to 84-yr-old participants in paired studies done before and at the end of a 2-wk weight-lifting program.
ISSN:0193-1849
1522-1555