A Case in Which Good Control of Carcinomatous Serositis Was Achieved Using Chemotherapy Including Albumin-Bound Paclitaxel(Nab-PTX)for Advanced-Stage Pulmonary Adenocarcinoma Exhibiting Carcinomatous Pleurisy and Carcinomatous Pericarditis

• Published in: Gan to kagaku ryoho Vol. 45; no. 8; p. 1181
• Main Authors: Tsujita, Tomohiro, Kuronuma, Keiichiro, Hata, Norihiko
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.08.2018
• Subjects: Adenocarcinoma - complications; Adenocarcinoma - drug therapy; Adenocarcinoma of Lung; Albumin-Bound Paclitaxel - administration & dosage; Albumins - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Humans; Lung Neoplasms - complications; Lung Neoplasms - drug therapy; Male; Middle Aged; Paclitaxel - administration & dosage; Pericarditis - etiology; Pleurisy - etiology; Serositis - etiology
• ISSN: 0385-0684

The subject was a 63-year-old man. The patient was transported by ambulance to the hospital because of dyspnea caused by carcinomatous pleurisy and carcinomatous pericarditis, after which pericardial drainage was performed; however, Staphylococcus aureus bacteremia arose as a complication. Adequate control of carcinomatous serositis was achieved usingchemotherapy, includingalbumin -bound paclitaxel(nab-PTX), which is a nanoparticle formulation bindinghuman serum albumin and paclitaxel, in combination with 1 course of antibiotics. For cancerous serositis cases, platinum combination chemotherapy usingnab -PTX is believed to be 1 treatment option in which good disease control can be expected along with bevacizumab, whose efficacy has already been confirmed.