A descriptive analysis of hyperlipidemia in adult twins in China

To describe the distribution characteristics of hyperlipidemia in adult twins in the Chinese National Twin Registry (CNTR) and explore the effect of genetic and environmental factors on hyperlipidemia. Twins recruited from the CNTR in 11 project areas across China were included in the study. A total...

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Published inZhōnghuá liúxíngbìng zázhì Vol. 44; no. 4; p. 544
Main Authors Miao, K, Cao, W H, Lyu, J, Yu, C Q, Wang, S F, Huang, T, Sun, D J Y, Liao, C X, Pang, Y J, Pang, Z C, Yu, M, Wang, H, Wu, X P, Dong, Z, Wu, F, Jiang, G H, Wang, X J, Liu, Y, Deng, J, Lu, L, Gao, W J, Li, L M
Format Journal Article
LanguageChinese
Published China 10.04.2023
Subjects
Adult
China - epidemiology
Diseases in Twins - genetics
Female
Humans
Hyperlipidemias - epidemiology
Hyperlipidemias - genetics
Male
Metabolic Diseases
Middle Aged
Twins, Dizygotic
Twins, Monozygotic - genetics
Young Adult
China
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Abstract To describe the distribution characteristics of hyperlipidemia in adult twins in the Chinese National Twin Registry (CNTR) and explore the effect of genetic and environmental factors on hyperlipidemia. Twins recruited from the CNTR in 11 project areas across China were included in the study. A total of 69 130 (34 565 pairs) of adult twins with complete information on hyperlipidemia were selected for analysis. The random effect model was used to characterize the population and regional distribution of hyperlipidemia among twins. The concordance rates of hyperlipidemia were calculated in monozygotic twins (MZ) and dizygotic twins (DZ), respectively, to estimate the heritability. The age of all participants was (34.2±12.4) years. This study's prevalence of hyperlipidemia was 1.3% (895/69 130). Twin pairs who were men, older, living in urban areas, married,had junior college degree or above, overweight, obese, insufficient physical activity, current smokers, ex-smokers, current drinkers, and ex-drinkers had a hig
AbstractList To describe the distribution characteristics of hyperlipidemia in adult twins in the Chinese National Twin Registry (CNTR) and explore the effect of genetic and environmental factors on hyperlipidemia. Twins recruited from the CNTR in 11 project areas across China were included in the study. A total of 69 130 (34 565 pairs) of adult twins with complete information on hyperlipidemia were selected for analysis. The random effect model was used to characterize the population and regional distribution of hyperlipidemia among twins. The concordance rates of hyperlipidemia were calculated in monozygotic twins (MZ) and dizygotic twins (DZ), respectively, to estimate the heritability. The age of all participants was (34.2±12.4) years. This study's prevalence of hyperlipidemia was 1.3% (895/69 130). Twin pairs who were men, older, living in urban areas, married,had junior college degree or above, overweight, obese, insufficient physical activity, current smokers, ex-smokers, current drinkers, and ex-drinkers had a hig
Author Liu, Y
Lyu, J
Yu, M
Wang, S F
Huang, T
Deng, J
Pang, Y J
Yu, C Q
Cao, W H
Jiang, G H
Li, L M
Wu, F
Wang, X J
Lu, L
Dong, Z
Gao, W J
Wang, H
Liao, C X
Sun, D J Y
Wu, X P
Miao, K
Pang, Z C
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  organization: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
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  organization: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
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  organization: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
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  organization: Qingdao Municipal Center for Disease Control and Prevention, Qingdao 266033, China
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  organization: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China
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  surname: Wang
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  organization: Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
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  surname: Wu
  fullname: Wu, X P
  organization: Sichuan Center for Disease Control and Prevention, Chengdu 610041, China
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  surname: Dong
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  organization: Beijing Center for Disease Prevention and Control , Beijing 100013, China
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  organization: Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
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  organization: Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China
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  organization: Qinghai Center for Disease Prevention and Control , Xining 810007, China
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  organization: Heilongjiang Provincial Center for Disease Control and Prevention, Harbin 150090, China
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  organization: Handan Center for Disease Control and Prevention of Hebei Province, Handan 056001, China
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  organization: Yunnan Center for Disease Control and Prevention, Kunming 650034, China
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  surname: Li
  fullname: Li, L M
  organization: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
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Snippet To describe the distribution characteristics of hyperlipidemia in adult twins in the Chinese National Twin Registry (CNTR) and explore the effect of genetic...
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SubjectTerms Adult
China - epidemiology
Diseases in Twins - genetics
Female
Humans
Hyperlipidemias - epidemiology
Hyperlipidemias - genetics
Male
Metabolic Diseases
Middle Aged
Twins, Dizygotic
Twins, Monozygotic - genetics
Young Adult
Title A descriptive analysis of hyperlipidemia in adult twins in China
URI https://www.ncbi.nlm.nih.gov/pubmed/37147824
Volume 44
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