The method for early diagnosis of the gastric cancer based metabolomics research

This paper deals with the questions of the usage of metabolomics research results in the diagnosis of gastric cancer. The central idea metabolomics is to identify the specific biomarkers in a biological sample used in a diagnostics this disease. The volatile organic compounds--metabolites isolated f...

Full description

Saved in:
Bibliographic Details
Published inĖksperimental'nai͡a︡ i klinicheskai͡a︡ gastroėnterologii͡a no. 10; p. 14
Main Authors Furina, R R, Ryzhkov, V L, Mitrakova, N N, Koptina, A V, Safiullin, I K, Lychagin, K A, Eroshkin, P R
Format Journal Article
LanguageRussian
Published Russia (Federation) 2014
Subjects
Biomarkers, Tumor - urine
Early Detection of Cancer - instrumentation
Early Detection of Cancer - methods
Gas Chromatography-Mass Spectrometry
Humans
Metabolome
Metabolomics - instrumentation
Metabolomics - methods
Solid Phase Microextraction
Stomach Neoplasms - urine
Volatile Organic Compounds - urine
Online AccessGet more information

Cover

More Information
Summary:This paper deals with the questions of the usage of metabolomics research results in the diagnosis of gastric cancer. The central idea metabolomics is to identify the specific biomarkers in a biological sample used in a diagnostics this disease. The volatile organic compounds--metabolites isolated from the urine samples from patients are considered as biomarkers. The paper also describes main methods of separation and identification of volatile organic compounds (gas chromatography, mass spectrometry) applied in metabolomics. The paper presents some results of laboratory research aimed at the detection of biomarkers of gastric cancer. The presented material will be of some help in solving the problems of early diagnosis of this disease.
ISSN:1682-8658