68Ga-DOTA-PET for neuroendocrine tumours

Neuroendocrine tumors (NET) are found in several organs and called NET tumors. They are relatively rare, most of them giving no symptoms and remaining undetected. Most NETs arise from the gut, stomach and bronchus. These tumors are diagnosed either by histology or by imaging. A typical feature of NE...

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Bibliographic Details
Published inDuodecim (Helsinki, Finland : 1961) Vol. 130; no. 19; p. 1931
Main Authors Loimaala, Antti, Mäenpää, Hanna, Lipponen, Tiina, Schildt, Jukka, Kämäräinen, Eeva-Liisa, Karhumäki, Lauri, Ahonen, Aapo
Format Magazine Article
LanguageFinnish
Published Finland 2014
Subjects
Humans
Neuroendocrine Tumors - diagnostic imaging
Octreotide - analogs & derivatives
Octreotide - chemical synthesis
Organometallic Compounds - chemical synthesis
Positron-Emission Tomography - methods
Radiopharmaceuticals - chemical synthesis
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Summary:Neuroendocrine tumors (NET) are found in several organs and called NET tumors. They are relatively rare, most of them giving no symptoms and remaining undetected. Most NETs arise from the gut, stomach and bronchus. These tumors are diagnosed either by histology or by imaging. A typical feature of NETs is abundance of somatostatin receptors on the cell surface, which makes it possible to image the tumor by nuclear methods as well as estimate the response to treatment by somatostatin analogues ("theranostics"). In order to improve the diagnosis of NETs we started to produce 68Ga-DOTA peptides for PET.
ISSN:0012-7183