Role of salivary mucin in the protection of rat esophageal mucosa from acid and pepsin-induced injury

The mucosal defensive mechanisms of the esophagus against acid and pepsin remain to be elucidated. In the present study, we investigated the contribution of the salivary mucin in maintaining the integrity of the esophageal mucosa.

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Bibliographic Details
Published inAmerican journal of physiology: Gastrointestinal and liver physiology Vol. 40; no. 4; pp. G796 - G800
Main Authors KINOSHITA, M, KUME, E, IGARASHI, S, SAITO, N, NARITA, H
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Physiological Society 01.10.1999
Subjects
Biological and medical sciences
Digestive system
Esophagus
Gastroenterology. Liver. Pancreas. Abdomen
Medical sciences
Other diseases. Semiology
Proteins
Rodents
Throat
Gastroesophageal reflux
Rat
Digestive system
Enzyme
Mucosa
Pepsin A
Esophageal disease
Rodentia
Salivary gland
Esophagus
Peptidases
Vertebrata
Mammalia
Mucin
Acids
Animal
Digestive diseases
Hydrolases
Aspartic endopeptidases
Lesion
Protection
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Summary:The mucosal defensive mechanisms of the esophagus against acid and pepsin remain to be elucidated. In the present study, we investigated the contribution of the salivary mucin in maintaining the integrity of the esophageal mucosa.
ISSN:0193-1857
1522-1547