The study on biological exposure index of occupational exposure to arsenic and its inorganic compounds

• Published in: Zhonghua laodong weisheng zhiyebing zazhi Vol. 42; no. 2; p. 84
• Main Authors: Shen, Y, Liu, J, Chou, X, Ma, K P, Sun, D Y, Min, Z
• Format: Journal Article
• Language: Chinese
• Published: China 20.02.2024
• Subjects: Arsenic - urine; Arsenicals; China; Humans; Occupational Exposure - analysis; China; Occupational exposure; Monomethyl arsenic (MMA); Inorganic arsenic; Biological exposure index; Dimethyl arsenic (DMA)
• ISSN: 1001-9391
• DOI: 10.3760/cma.j.cn121094-20230703-00229

To establish biological exposure index (BEI) of occupational exposure to arsenic and its inorganic compounds through occupational epidemiology and the regression analysis of internal and external exposure of workers. In November 2021, 125 workers with occupational exposure to arsenic and its inorganic compounds and 49 office administrators in a non-ferrous metal smelter in Yunnan Province were selected as the exposure group and control group, respectively. Air samples from the workplace of the study subjects on weekdays were collected and arsenic concentrations were determined. Urine samples were collected in end-of-work weekend and high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) was used to detect the levels of trivalent inorganic arsenic (iAs(3+)) , pentavalent inorganic arsenic (iAs(5+)) , monomethyl arsenic (MMA) and dimethyl arsenic (DMA) in urine. The correlations between arsenic concentration in the workplace air and arsenic species in urine of workers