MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT OF CHEMOTHERAPY TOXICITY IN PATIENTS WITH BREAST CANCER

The use of modern chemotherapy (CT) allowed to achieve significant progress in the treatment of many malignant tumors that were previously considered fatal. Improving the efficiency of the treatment was achieved by the intensification of chemotherapy. However, intensification of chemotherapy regimes...

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Bibliographic Details
Published inLikars'ka sprava no. 3-4; pp. 3 - 15
Main Authors Syvak, L A, Hubareva, H O, Filonenko, K S, Majdanevych, N M, Aleksyk, O M, Lyalkin, S A, Klimanov, M J, Askolskyi, A V, Kasap, N V
Format Journal Article
LanguageUkrainian
Published Ukraine 01.04.2015
Subjects
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - adverse effects
Antineoplastic Combined Chemotherapy Protocols
Breast Neoplasms - drug therapy
Breast Neoplasms - metabolism
Breast Neoplasms - pathology
Chemical and Drug Induced Liver Injury - diagnosis
Chemical and Drug Induced Liver Injury - drug therapy
Chemical and Drug Induced Liver Injury - metabolism
Female
Humans
Nausea - chemically induced
Nausea - diagnosis
Nausea - drug therapy
Nausea - metabolism
Neutropenia - chemically induced
Neutropenia - diagnosis
Neutropenia - drug therapy
Neutropenia - metabolism
Protective Agents - therapeutic use
Receptors, Serotonin - metabolism
Serotonin Antagonists - therapeutic use
Vomiting - chemically induced
Vomiting - diagnosis
Vomiting - drug therapy
Vomiting - metabolism
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Summary:The use of modern chemotherapy (CT) allowed to achieve significant progress in the treatment of many malignant tumors that were previously considered fatal. Improving the efficiency of the treatment was achieved by the intensification of chemotherapy. However, intensification of chemotherapy regimes provoked increase in the number of side effects of anticancer therapy,which often lead to a decrease in the intensity of the selected mode, the additional financial costs of treating the complications and the formation of the negative attitude of the patient to treatment. Thus, the side effects of chemotherapy are the actual problem of modern oncology. The purpose of this literature review was to investigate the frequency, symptoms and ways to prevent and treat various types of toxicity of chemotherapy.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1019-5297