Clinical case of the month. A rare case of arthritis and fever
We present the case report ofa 28 year old male presenting with recurrent fever episodes and arthralgia. Based on the presence of an inflammatory syndrome, a hyperferritinemia, a salmon-pink rash and recurrent fever episodes, the diagnosis of an adult onset Still's disease (AOSD) was made. A tr...
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Published in | Revue médicale de Liège Vol. 68; no. 7-8; p. 423 |
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Main Authors | , , , |
Format | Journal Article |
Language | French |
Published |
Belgium
01.07.2013
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Subjects | |
Online Access | Get more information |
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Summary: | We present the case report ofa 28 year old male presenting with recurrent fever episodes and arthralgia. Based on the presence of an inflammatory syndrome, a hyperferritinemia, a salmon-pink rash and recurrent fever episodes, the diagnosis of an adult onset Still's disease (AOSD) was made. A treatment with corticosteroids was started. During the following years, the corticosteroids could not be tapered. Eventually, a treatment with anakinra, an interleukin 1 (IL-1) receptor antagonist was started, allowing tapering of the corticosteroids. This case report supports the possible role of IL-1 in the pathogenesis ofAOSD, possibly through the inflammasome. |
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ISSN: | 0370-629X |