Comparison between approximate entropy and regional homogeneity for identification of irritable bowel syndrome based on functional magnetic resonance imaging

• Published in: Nan fang yi ke da xue xue bao = Journal of Southern Medical University Vol. 39; no. 9; p. 1023
• Main Authors: Nan, Jiaofen, Zhang, Liangliang, Zheng, Qian, Zhang, Minghui, Lu, Zhentai
• Format: Journal Article
• Language: Chinese
• Published: China 30.09.2019
• Subjects: Brain - diagnostic imaging; Brain Mapping; Case-Control Studies; Entropy; Humans; Irritable Bowel Syndrome - diagnostic imaging; Magnetic Resonance Imaging; resting state; approximate entropy; regional homogeneity; irritable bowel syndrome; functional magnetic resonance imaging
• ISSN: 1673-4254
• DOI: 10.12122/j.issn.1673-4254.2019.09.04

To compare the effectiveness and sensitivity of entropy and regional homogeneity (ReHo) for identifying irritable bowel syndrome (IBS) based on functional magnetic resonance imaging (fMRI). Voxel-based approximate entropy (ApEn) was calculated based on findings of resting fMRI of 54 patients with IBS and 54 healthy control subjects. Feature selection was performed using independent sample -test, and support vector machine was then used to classify and identify different groups. The classification performance obtained from ApEn was compared with that from ReHo. Significant differences between the two groups were found in the left triangle part of inferior prefrontal gyrus, right angular gyrus of the inferior parietal lobule, left inferior temporal gyrus, left middle temporal gyrus, left lingual gyrus, bilateral middle occipital gyrus and bilateral superior occipital gyrus for ReHo ( < 0.05), and in the bilateral postcentral gyrus, right precentral gyrus, right inferior temporal gyrus, bilateral middle temporal