Features of anesthesia in rats at abdominal operations

Nowadays, in Russia, diethyl ether is the most popular narcosis for rodent and particular rats. We had tested the new methods based on Zoletil 100 + XylaVet (15 mg/kg and 15-10-5 mg/kg) respectively. 6 conventional female rats were treated with this narcosis. The rats, early have narcotized by dieth...

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Bibliographic Details
Published inĖksperimental'nai͡a︡ i klinicheskai͡a︡ gastroėnterologii͡a no. 5; p. 62
Main Authors Smirnova, A V, Lagutina, L D, Trubitsina, I E, Vasnev, O S, Ianova, O B
Format Journal Article
LanguageRussian
Published Russia (Federation) 2012
Subjects
Anesthesia, General - adverse effects
Anesthesia, General - methods
Anesthetics - adverse effects
Anesthetics - pharmacology
Animals
Budd-Chiari Syndrome - chemically induced
Digestive System Surgical Procedures - adverse effects
Digestive System Surgical Procedures - methods
Drug Combinations
Female
Postoperative Complications - chemically induced
Rats
Tiletamine - adverse effects
Tiletamine - pharmacology
Zolazepam - adverse effects
Zolazepam - pharmacology
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Summary:Nowadays, in Russia, diethyl ether is the most popular narcosis for rodent and particular rats. We had tested the new methods based on Zoletil 100 + XylaVet (15 mg/kg and 15-10-5 mg/kg) respectively. 6 conventional female rats were treated with this narcosis. The rats, early have narcotized by diethyl ether were investigated as control group. All of 6 treated with new narcosis animals died in early post-operative time. Interestingly enough, that organ toxicity, except neurologic toxicity, was not described in literature and manuals. We assume that this new narcosis is the cause of portal thromboses.
ISSN:1682-8658