Clinical and pathologic analysis of 414 cases of renal angiomyolipomain in a single institution

• Published in: Zhonghua bing li xue za zhi Vol. 46; no. 6; p. 378
• Main Authors: Bao, H L, Chen, X, An, Y X, Sun, H B, Wang, H Y, Guo, A T
• Format: Journal Article
• Language: Chinese
• Published: China 08.06.2017
• Subjects: Adolescent; Adult; Aged; Angiomyolipoma - complications; Angiomyolipoma - epidemiology; Angiomyolipoma - pathology; Carcinoma, Renal Cell - pathology; Female; Hematuria - etiology; Humans; Kidney; Kidney Neoplasms - complications; Kidney Neoplasms - epidemiology; Kidney Neoplasms - pathology; Male; Middle Aged; Necrosis; Prognosis; Retrospective Studies; Young Adult; Immunohistochemistry; Kidney neoplasm; Prognosis
• ISSN: 0529-5807
• DOI: 10.3760/cma.j.issn.0529-5807.2017.06.003

To study the different clinicopathological characteristics between classic and epithelioid renal angiomyolipoma, and the relationships between clinicopathological characteristics and biological behaviors as basis for clinical treatment. The clinicopathological and follow-up data for the patients diagnosed with renal angiomyolipoma between 2004 and 2011 were retrospectively reviewed and analyzed. There were 414 cases of renal angiomyolipoma diagnosed over 8 years ago, accounting for 8.1% (414/5 287) of all renal parenchymal tumors. The patients included 122 male and 292 female (male-to-female ratio of 1.0∶2.4), mean age 44.0 years (range 15-74 years). Of these, 195(47.1%) tumors occurred in the left kidney, 212(51.2%) in the right kidney and seven (1.7%) were bilateral. Clinically, some cases presented with hypochondrial pain, hematuria or palpable masses. Histologically, 394(95.2%) were classic angiomyolipoma, 20(4.8%) were epithelioid angiomyolipoma; 54, 23 and 7 cases had hemorrhage, necrosis and cystic deg