Participation rate and detection of colorectal neoplasms based on multi-round fecal immunochemical testing for colorectal cancer screening in the Chinese population

• Published in: Zhōnghuá zhŏngliú zázhì Vol. 45; no. 12; pp. 1041 - 1050
• Main Authors: Li, N, Zhou, Y Y, Lu, M, Zhang, Y H, Lu, B, Luo, C Y, Luo, J H, Cai, J, Chen, H D, Dai, M
• Format: Journal Article
• Language: Chinese
• Published: China 23.12.2023
• Subjects: Adenoma - diagnosis; Colonoscopy; Colorectal Neoplasms - pathology; Early Detection of Cancer; Female; Humans; Male; Mass Screening; Predictive Value of Tests; Fecal occult blood testing; Detection rate; Participation; Screening; Colorectal neoplasms
• ISSN: 0253-3766
• DOI: 10.3760/cma.j.cn112152-20230221-00073

To evaluate the participation rate and detection of colorectal neoplasms based on annual fecal immunochemical testing (FIT) for three consecutive years in a population-based colorectal cancer screening program in China. Based on a population-based colorectal cancer screening program conducted from May 2018 to May 2021 in 6 centers in China, 7 793 eligible participants aged 50-74 were included and offered free FIT and colonoscopy (for those who were FIT-positive on initial screening). At baseline, all participants were invited to receive FIT. In subsequent screening rounds, only FIT-positive participants who did not undergo colonoscopy or FIT-negative participants were invited to have repeated FIT screening. FIT-positive participants were recommended to undertake colonoscopy and pathological examination (if abnormalities were found during colonoscopy). An overall of three rounds of annual FIT screening were conducted. The primary outcomes of the study were the participation rate of FIT screening, the complianc