Gene editing technology and its research progress in China

Gene editing is a technology for precision modification of genome sequences or expressing transcripts. Early versions of such techniques include homing endonuclease, zinc finger endonuclease and transcription-like activator effectors. The CRISPR/Cas9 system has recently emerged as a powerful and ver...

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Bibliographic Details
Published inYíchuán Vol. 40; no. 10; p. 900
Main Authors Chen, Yi Ou, Bao, Ying, Ma, Hua Zheng, Yi, Zong Yi, Zhou, Zhuo, Wei, Wen Sheng
Format Journal Article
LanguageChinese
Published China 20.10.2018
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Summary:Gene editing is a technology for precision modification of genome sequences or expressing transcripts. Early versions of such techniques include homing endonuclease, zinc finger endonuclease and transcription-like activator effectors. The CRISPR/Cas9 system has recently emerged as a powerful and versatile gene editing tool for a broad spectrum of applications. In this review, we discuss the recent development and applications of gene editing technology, and particularly focus on the progress in China, with the emphasis on mechanistic studies, development of new and extended technologies, the applications in animals, plants and the therapeutics.
ISSN:0253-9772
DOI:10.16288/j.yczz.18-195